When should you hold Aranesp?
For Pediatric Patients With CKD Initiate Aranesp treatment when the hemoglobin level is less than 10 g/dL. If the hemoglobin level approaches or exceeds 12 g/dL, reduce or interrupt the dose of Aranesp.
What labs are needed for Aranesp?
You may be asked to have certain blood tests, such as hemoglobin, hematocrit or blood iron levels. Also, your doctor may prescribe iron for you to take. Follow your doctor’s orders.
How often should Aranesp be given?
Aranesp® may be given as a subcutaneous (under the skin) injection or rarely into a vein (intravenous). It is typically administered every two weeks, allowing patients to visit their doctor less frequently and avoid unnecessary injections. Increased red blood cell levels in response to Aranesp® may take several weeks.
What should I monitor with Epogen?
Your doctor will test your blood regularly—at least weekly at the beginning of your treatment—to make sure EPOGEN® is working. The test will measure your Hb or your hematocrit (hee-MAT-a-crit) levels, though most doctors measure Hb because it is a better way to check for anemia.
When should you not give Aranesp injection?
Do not use Aranesp: – if you are allergic to darbepoetin alfa or any of the other ingredients of this medicine listed in section 6. – if you have been diagnosed with high blood pressure which is not being controlled with other medicines prescribed by your doctor.
What are the side effects of Aranesp?
Common side effects of Aranesp include:
- body aches,
- stomach pain,
- skin rash or redness,
- diarrhea, and.
- injection site reactions (pain, bruising, swelling, warmth, redness, oozing, or bleeding).
What is the medication Aranesp used for?
Aranesp (darbepoetin alfa) is an erythropoiesis-stimulating agent, or ESA, used to treat anemia (a lack of red blood cells in the body) in people with long-term serious kidney disease (chronic renal failure) and people receiving chemotherapy for some types of cancer.
How is Aranesp administered?
Aranesp can be injected directly into a layer of fat under your skin. This is called a subcutaneous injection. When giving subcutaneous injections, follow your healthcare provider’s instructions about changing the site for each injection.
What is Aranesp used to treat?
How do you administer Aranesp?
Aranesp can be injected directly into a layer of fat under your skin. This is called a subcutaneous injection. When giving subcutaneous injections, follow your healthcare provider’s instructions about changing the site for each injection. You may wish to write down the site where you have injected.
Which monitoring is required for erythropoietin therapy?
As anemia improves, continued monitoring of hematocrit, hemoglobin, red cell indices, serum ferritin level, and transferrin percent saturation will ensure that depleted iron stores are noted and treated as necessary.
What is the difference between Epogen and Aranesp?
Epoetin alfa (Retacrit, Procrit, Epogen) is a glycoprotein that stimulates red blood cell production; whereas, darbepoetin alfa (Aranesp) stimulates erythropoiesis by the same mechanism as endogenous erythropoietin.
What lab values should be monitored with epoetin alfa?
Monitoring and Testing While Taking Epoetin Alfa You will be monitored regularly by your doctor while you are taking epoetin alfa. Tests will include blood tests (specifically hemoglobin and hematocrit) and blood pressure measurements.
What are the benefits of Aranesp?
Darbepoetin alfa also helps to reduce the need for blood transfusions. It works by signaling the bone marrow to make more red blood cells. This medication is very similar to the natural substance in your body (erythropoietin) that prevents anemia.
How safe is Aranesp?
Aranesp increases the risk of death, myocardial infarction, stroke, venous thromboembolism, and thrombosis of vascular access and tumor progression or recurrence. Aranesp can also lead to an increase in adverse cardiovascular events, hypertension, seizures, and severe anemia.
How effective is Aranesp?
SAN FRANCISCO-The anemia drug darbepoetin alfa (ARANESP) effectively alleviates anemia, boosting hemoglobin counts and reducing the need for red blood cell transfusions, according to the results of two separate studies.
How do you give a hemoglobin injection?
Adults—Dose is based on body weight and must be determined by your doctor. The starting dose is 100 units per kilogram (kg) injected into a vein or under the skin three times a week for 8 weeks. Your doctor may adjust the dose as needed. Children—Use and dose must be determined by your doctor.