What are the zones of cartilage?
Nanomaterials for cartilage tissue engineering Articular cartilage can be divided into four zones depending on the collagen and proteoglycan organization and content: the superficial zone, the transitional zone, the middle (radial) or deep zone, and the calcified cartilage zone (Fig. 11.2) (Umlauf et al., 2010).
How many zones are in the articular cartilage?
Along with collagen fiber ultrastructure and ECM, chondrocytes contribute to the various zones of articular cartilage—the superficial zone, the middle zone, the deep zone, and the calcified zone (Figure 2).
What happens in the zone of proliferating cartilage?
Zone of proliferation: Chrondrocytes are stacked in prominent rows and the cartilage matrix becomes more basophilic in this zone. Mitotic figures are present and the axis of the mitotic figure usually is perpendicular to that of the row of chondrocytes.
What is the zone of hypertrophy?
The zone of maturation and hypertrophy contains chondrocytes that are older and larger than those in the proliferative zone. The more mature cells are situated closer to the diaphyseal end of the plate. In this zone, lipids, glycogen, and alkaline phosphatase accumulate, causing the cartilaginous matrix to calcify.
What are the 4 zones of the epiphyseal plate?
Terms in this set (4)
- Proliferation Zone. Zone 1. Cartilage cells undergo mitosis.
- Hypertrophic Zone. Zone 2. Older cartilage cells enlarge.
- Calcification Zone. Zone 3. Matrix becomes calcified; cartilage cells die; matrix begins deteriorating.
- Ossification Zone. Zone 4. New bone formation is occurring.
What are the 5 zones of the epiphyseal plate?
Study each of the five zones of the epiphyseal plate:
- Zone of Reserve Cartilage (RC).
- Zone of Proliferating Cartilage (PC).
- Zone of Hypertrophic Cartilage (HC).
- Zone of Calcified Cartilage (CC).
- Zone of Ossification (Resorption)(OSS).
What are the different layers of cartilage?
The surface of most cartilage is covered by a layer of dense irregular connective tissue called the perichondrium (peri = around). The outer layer of the perichondrium contains collagen producing fibroblasts, and the inner layer contains chondroblasts.
What are types of cartilage?
There are three types of cartilage: hyaline, fibrous, and elastic cartilage. Hyaline cartilage is the most widespread type and resembles glass. In the embryo, bone begins as hyaline cartilage and later ossifies.
What are the four zones of the epiphyseal growth plate?
4 Cards in this Set
| Zone of Reserve Cartilage | closest to epiphysis* anchor plate to epiphyseal bone |
|---|---|
| Zone of Proliferating Cartilage | 2nd closest to epiphysis* chondrocytes stacked, replacing dead cells at diaphyseal surface |
| Zone of Hypertrophic Cartilage | 3rd closest to epiphysis* chondrocytes form mature cartilage |
What are the 4 zones of the bone?
High Magnification
- Zone of Reserve Cartilage (RC).
- Zone of Proliferating Cartilage (PC).
- Zone of Hypertrophic Cartilage (HC).
- Zone of Calcified Cartilage (CC).
- Zone of Ossification (Resorption)(OSS).
What are the four zones of cartilaginous cells at the epiphyseal plate during endochondral ossification?
In endochondral ossification: The bone is formed onto a temporary cartilage model. The cartilage model grows (zone of proliferation), then chondrocytes mature (zone of maturation) and hypertropy (zone of hypertrophy), and growing cartilage model starts to calcify.
What are the zones of bone growth?
Where are dividing cartilage cells located?
On the epiphyseal side of the epiphyseal plate, hyaline cartilage cells are active and are dividing and producing hyaline cartilage matrix.
What are the 4 functions of cartilage?
Cartilage has many functions, including the ability to resist compressive forces, enhance bone resilience, and provide support on bony areas where there is a need for flexibility. The primary cell that makes cartilage is the chondrocyte, which resides within the lacunae.
What zone are cartilage cells rapidly dividing?
In the growth plate, stem-like cells in the resting zone differentiate into rapidly dividing chondrocytes in the proliferative zone and then terminally differentiate into nondividing chondrocytes of the hypertrophic zone.
What are the four zones of cartilage found within the growth plate?
What are the 5 zones of bone growth?
resting zone, 2. proliferation zone, 3. hypertrophic cartilage zone, 4. calcified cartilage zone, and 5.